N K Aggarwal Joints And Spine Centre

Platelet-Derived Growth Factors for Knee Pain: A Natural Path to Healing

veerpal sharma on July 10, 2025

Platelet-Derived Growth Factors for Knee Pain: A Natural Path to Healing

At N. K. Aggarwal Joints & Spine Centre, we believe in combining cutting-edge science with compassionate care to help patients regain movement, reduce pain, and avoid unnecessary surgeries. One of the most exciting breakthroughs in regenerative medicine today is the use of Platelet-Derived Growth Factors (PDGFs) to treat knee pain and joint degeneration.

What Is Platelet-Derived Growth Factors (PDGFs)

PDGFs are powerful, naturally occurring proteins found in platelets, tiny cells in your blood that play a central role in healing. These growth factors are responsible for stimulating cell repair, reducing inflammation, and encouraging tissue regeneration. In Orthopaedic medicine, PDGFs are commonly delivered through Platelet-Rich Plasma (PRP) therapy. PDGFs are extracted in a concentrated form, from these platelets and are there therefore a step ahead of conventional PRP.
PRP is created by drawing a small amount of a patient’s own blood and processing it in a centrifuge to concentrate the platelets and then PDGFs are extracted from the platelets. The final product rich in PDGFs and other regenerative proteins, then carefully injected into the affected knee joint to promote healing from within. Usually, three doses PDGF injections are advised, each around 20 days apart.

Why Use PDGFs for Knee Pain?

PDGF therapy is particularly beneficial for patients dealing with:

  • Early to moderate knee osteoarthritis
  • Cartilage degeneration or thinning
  • Meniscus injuries
  • Chronic inflammation or joint stiffness
  • Ligament sprains or strain-related pain

Unlike temporary solutions such as steroid injections or long-term medications, PDGF therapy targets the underlying issue, stimulating actual tissue repair rather than just masking pain.

How the Procedure Works at N. K. Aggarwal Joints & Spine Centre

Under the expertise of Dr. N. K. Aggarwal, Senior Orthopaedic and Spine Surgeon, PDGF procedures are performed using a precise technique. This ensures that the injection reaches the exact area in need of regeneration.
Dr. Aggarwal explains:
“Platelet-derived growth factors are like the body’s natural repair kit. When introduced into a damaged joint, they wake up dormant healing pathways, often with results that exceed conventional treatments especially in early-stage arthritis.”
The entire process takes about 45–60 minutes, and because the therapy uses the patient’s own blood, the risk of allergic reaction or rejection is extremely low.

Key Benefits of PDGF Therapy

  • Minimally invasive and safe
  • No need of admission or anaesthesia
  • Reduces pain and inflammation
  • Improves joint mobility and function
  • Stimulates long-term tissue repair
  • Delays or eliminates need for joint surgery
  • Quick recovery with minimal downtime
  • Can be easily repeated if necessary after few years

Patients typically begin to notice improvement within 4-8 weeks, with continued benefits over several years.

Why Choose Joints & Spine Centre?

Dr. N.K. Aggarwal and his team are pioneers in Regenerative Orthopaedics in India, offering customized care plans, scientifically-backed therapies, and decades of surgical and non-surgical expertise. Every treatment is tailored to the individual, ensuring the highest level of safety and results.

Take the Next Step

If knee pain is affecting your quality of life, you don’t have to wait for it to worsen. Book a consultation today with Dr. N. K. Aggarwal at Joints & Spine Centre to find out if Platelet-Derived Growth Factor therapy is right for you.


Heal naturally. Move freely. Live fully.

Source 1. National Institutes of Health (NIH) / PubMed

  1. Journal of Orthopaedic Surgery and Research (Springer Open)
  2. American Academy of Orthopaedic Surgeons (AAOS)

Knee Pain Treatment Without Joint Replacement Surgery:Is It Possible?

veerpal sharma on July 2, 2025

Knee Pain Treatment Without Joint Replacement Surgery:
Is It Possible?

Knee pain has a way of quietly taking over your life, turning every step into a struggle, every staircase into a challenge, and every morning into a reminder of what you can no longer do. For many, the idea of surgery brings more fear than relief.But what if there was a way to treat knee pain without replacing the joint?


At N.K. Aggarwal Joint and Spine Centre, we’re changing the way people think about knee care with PRP and PRP derived Growth Factors’ therapy, a powerful alternative to knee replacement, along with other measures.

The Breakthrough You’ve Been Waiting For

Platelet-Rich Plasma and Platelet Derived Growth Factors’ Therapy is a science-backed, non-surgical treatment that uses your body’s own healing potential to repair damaged joints. Here’s how it works:

  • A small amount of your blood is drawn and spun in a centrifuge to separate the platelets.
  • These concentrated platelets rich in growth and healing factors or growth factor concentrate derived from these platelets, are injected into your knee.
  • The body responds by naturally reducing inflammation, repairing damaged tissues, and regenerating joint health.

Other adjuvants to this therapy, like Arthroscopic Knee lavage, Lubricant (Hyaluronic acid) injection and correction of any deformity are added to treatment as necessary. Regular knee exercises (Physiotherapy) and necessary medications are also part of any treatment of knee pain.

What does that mean for you? Less pain, more movement, and no need to go under the knife.

Why More Patients Are Choosing PRP and Growth factors Over Surgery

At N.K. Aggarwal Joint and Spine Centre, we’ve seen firsthand how this is transforming lives. It’s become a preferred choice for patients who:

  • Want to avoid the risks and downtime of surgery
  • Suffer from early to moderate osteoarthritis
  • Have chronic knee pain due to injury or degeneration
  • Are looking for a natural, long-term solution

Benefits of this Therapy:

  • Minimally invasive, no stitches, no hospital stay
  • Faster recovery and return to daily activities
  • No artificial implants or foreign substances
  • Stimulates actual healing, not just symptom relief
  • Cost-effective and safe
  • Can be easily repeated, if necessary, usually after 10-15 years

Personalized Care. Proven Results.

At N.K. Aggarwal Joint and Spine Centre, PRP isn’t just a procedure it’s part of a comprehensive healing journey. With expert diagnosis, precision-guided injections, and tailored follow-up, we ensure that each patient gets the care they truly need.

Led by Dr. N.K. Aggarwal, our team combines experience, compassion, and innovation making us one of the region’s most trusted names in joint care.

Real Stories. Real Recovery.

From busy professionals to elderly patients, countless individuals have chosen this treatment over knee replacement and reclaimed their freedom of movement. They’re walking without pain, climbing stairs with ease, and living life on their own terms again.

Is Knee Replacement Your Only Option? Not Anymore.

If you’ve been told that surgery is inevitable, don’t decide without exploring this therapy, also called Regenerative and Ortho biologic Therapy.
In many cases, acting early, this can delay or completely avoid knee replacement.

It’s time to move beyond pain.
Discover the Regenerative and Ortho biologic Therapy breakthrough at N.K. Aggarwal Joint and Spine Centre and step confidently into a future without surgery.

Top 5 Signs You Need to See a Spine Specialist

veerpal sharma on July 2, 2025

Top 5 Signs You Need to See a Spine Specialist

Introduction

We often disregard our spine until it causes problems. A dull ache or a sudden sharp pain can severely disrupt daily life. Your spine is central to everything you do, and ignoring its warning signs can lead to long-term harm. That’s why recognizing the right time to visit a specialist is crucial.

Dr. N.K. Aggarwal, an exceptional joint and spine expert and chief of the Joint and Spine Centre, has extensive experience. Having practiced for years with a dedicated focus on spinal health, he has treated thousands of patients. Here are the top 5 signs you should never ignore.

  1. Persistent Back or Neck Pain

    Back or neck pain is often attributed to stress or poor posture. However, pain that lasts for months or recurs frequently, could indicate a more serious issue, such as a herniated disc, arthritis, or spinal degeneration
    Performing daily activities becomes burdensome, sleep is disrupted, and standing or sitting becomes challenging. If quick fixes don’t work, it’s time to consult a spine specialist. Dr. Aggarwal uses advanced imaging and diagnostics to identify the root cause and create a personalized treatment plan.
  2. Numbness, Tingling, or Weakness in the Limbs

    If your arms or legs frequently feel numb, tingly, or weak, it could be more than poor blood circulation, possibly nerve compression. Common causes include spinal stenosis, bulging discs, or sciatica. Left untreated, these conditions can worsen over time and result in permanent nerve damage.
    At the N.K. Aggarwal Joint & Spine Centre, Dr. Aggarwal utilizes cutting-edge technology to accurately diagnose these conditions and provide effective non-surgical or minimally invasive treatments to relieve pressure and restore functionality.
  3. Involuntary Loss of Bladder or Bowel Control

    Sudden issues with bladder or bowel function can indicate Cauda Equina Syndrome, a complex condition requiring urgent attention. Don’t wait. Quick intervention can prevent lifelong damage.
  4.  Walking or Balance Problems

    If you find it difficult to walk straight, climb stairs, or maintain balance, you may be suffering from spinal cord compression or a neurological condition originating from the spine. Early diagnosis coupled with therapy can significantly improve mobility and minimize fall risk.
  5. Pain that radiates to other parts of the body

    Back or neck pain that shoots down your arms or legs is a red flag for irritated nerves. This can result from a bulging disc or a pinched nerve root. Treat the problem, not just the symptoms. A spine specialist can help avoid permanent nerve damage.

Conclusion

Your spine is the backbone of your body so don’t ignore what it’s telling you. Whether it’s chronic pain, strange sensations, or abrupt weakness, these are warning signs demanding expert attention. Dr. N.K. Aggarwal and his team at the Joint and Spine Centre are here to provide the correct diagnosis and treatment before it’s too late. The philosophy of treatment at this centre is to treat by simple methods first, with medications and physiotherapy. Only in refractory and complicated/advanced cases, surgery is done. This is usually in 5-10% of cases. 

Take control of your spine health today.

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